Sarcoidosis may in some cases be complicated by pleural nym effusion. Pleural effusion is formed in 1-2% of patients with sarcoidosis , although in one series of observations this figure was 7% . Patients with pleural effusion caused by sarcoidosis usually have extensive ny sarcoidosis parenchyma and often – extrathoracic sarcoidosis . The symptoms of pleural lesions are different, many patients may have an asymptomatic course , although in the same number of patients the disease is accompanied by pleural pain and shortness of breath.
In sarcoidosis, approximately in Ose patients effusion two third-party, in other cases – one – sided. The size of the pleural effusion is usually small, but in some cases it can be extensive. Pleural fluid usual but is an exudate with a predominance of small lim phocytes . In one paper, 7 cases of transudate in sarcoidosis were reported ; the pleural fluid protein content did not exceed 2.5 g / 100 ml . However, these data on the protein content is so at odds with those of other authors, that they can not be taken into account. In case of puncture or open pleural biopsy, noncaseating granulomas are found in this disease .
The diagnosis of pleural effusion caused by sarcoidosis follows blowing mean in patients with pleural effusion and two third-party infiltrates in the parenchyma. Detection of non-caseous granulomas during pleural biopsy is another evidence celia in favor of this diagnosis. However, it should be borne in mind that the majority of patients with pleural effusion and noncaseating granulomas suffer from tuberculosis rather than sarcoidosis . Detection of non-caseous granulomas during pleural biopsy may also indicate a fungal infection of the pleura . However, if a patient has infiltrates in the parenchyma and a typical symmetrical two-sided root adenopathy , tuberculin test otritsa well, and noncaseating granulomas are found both in the pleura and in the tissues, then, probably, in a patient with sarcoidosis . Given in favor The diagnosis shows an increase in serum angiotensin-converting enzyme. At le chenii pleuralsarcoidosis with corticosteroids there fast! the disappearance of symptoms of the disease (if any were absorbed) and resorption of pleural effusion .