Gastrointestinal manifestations of RA. The following symptoms are described on the part of the gastrointestinal tract: constipation (39%), flatulence (21%), nausea (15%), vomiting (11%), abdominal pain
(9.6%), diarrhea (3%). The most serious syndromes can be erosions and even ulcers of the stomach and intestines. Pathogenically, they are associated with vasculitis and trophic mucosal impairment. In addition, medicinal ulcers may occur as a result of the use of both steroid hormones and non-steroidal anti-inflammatory drugs (aspirin, etc.).
Neurological manifestations of RA. The nervous system in rheumatoid arthritis is naturally and permanently affected. It is known from the clinical picture of rheumatoid arthritis that already at the early stages of its development, increased fatigue, irritability, sleep disturbance, weight loss, tactile and
periatric paresthesias in the limbs, sweating of the hands and feet. These clinical manifestations indicate dysfunction of the central and peripheral nervous system, in particular, its vegetative divisions (3. S. Manelis, V. Ya. Bobylev et al., 1984). In an objective examination, according to numerous data from the literature, it is possible to reveal a picture of polyneuritis.
For lesions of the nervous system in rheumatoid arthritis, polymorphism of the clinical picture with damage to the entire cerebrospinal axis is characteristic. In patients with often ringing in the ears, dizziness, tremor, convulsions.