In a study of 600 febrile children aged 4 weeks to 2 years who were under observation in the emergency room, Teele found that 29% of them had a fever with no local symptoms or a fever with the symptoms of “upper respiratory tract infection”.
Unfortunately, he combined these two states into one group, although in other studies there was an almost threefold difference in the frequency of bacteremia in patients with no local symptoms as compared with patients with upper respiratory tract infection. Wright analyzed 300 cases of fever in children undergoing a complete clinical examination, and showed that 22% of them had no local signs or symptoms.
Based on a study of private pediatric practice in upstate New York, Hoekelman calculated that every practical pediatrician should meet one child with a fever with no local symptoms from 1 to 24 months every 4.6 days. A child with a temperature of 40 ° C and above should occur every 36.7 days.
In his study of the private pediatric practice, Baron showed that every 7.5 days he or his partner had to deal with one child aged 3 to 24 months with a fever with no local symptoms (one case per pediatrician every 15 days). Stein noted that the peak of the frequency of fever without local symptoms occurs in the 2nd year of life and decreases after the 3rd year. In his study of 200 cases, only 21 children were older than 10 years.
Thus, from 3.5 to 29% of children with fever have no focal or local symptoms of the disease. The exact numbers vary depending on the nature of the population studied and the local epidemiological situation. The average figure apparently ranges between 5 and 10%.